Green approach for synthesis of bioactive Hantzsch 1,4-dihydropyridine derivatives based on thiophene moiety via multicomponent reaction

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Green approach for synthesis of bioactive Hantzsch 1,4-dihydropyridine derivatives based on thiophene moiety via multicomponent reaction

A novel green and efficient one-pot multicomponent reaction of dihydropyridine derivatives was reported as having good to excellent yield. In the presence of the catalyst ceric ammonium nitrate (CAN), different 1,3-diones and same starting materials as 5-bromothiophene-2-carboxaldehyde and ammonium acetate were used at room temperature under solvent-free condition for the Hantzsch pyridine synt...

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sulfated titania nanoparticles: an efficient catalyst for the synthesis of polyhydroquinoline derivatives through hantzsch multicomponent reaction

sulfated titania nanoparticles (so42-/tio2 nps) were synthesized using titanium tetraisopropoxide (ttip) by the sol-gel method. the structure and morphology of the prepared nanocatalyst was characterized using x-ray diffraction (xrd), scanning electron microscopy (sem) and brunauer–emmett–teller (bet) methods as well as fourier transform infrared (ft-ir) and energy dispersive x-ray (edx) spectr...

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ژورنال

عنوان ژورنال: Royal Society Open Science

سال: 2017

ISSN: 2054-5703

DOI: 10.1098/rsos.170006